Tuberculosis, commonly called TB, can begin without noticeable symptoms. A cough that does not go away, unexplained weight loss, tiredness or repeated fever may seem like ordinary symptoms at first. But when these symptoms persist, they should not be ignored.

It most commonly affects the lungs, but it can also affect other parts of the body. Recognising the symptoms early and getting the appropriate tests can help doctors diagnose TB and begin treatment promptly. In this blog, let us understand more about TB, including its symptoms, causes, diagnosis and treatment.

What causes tuberculosis?

TB is caused by bacteria called Mycobacterium tuberculosis. It usually spreads through the air when a person with infectious TB of the lungs or throat coughs, sneezes or speaks.

Not everyone who becomes infected develops active TB disease. Some people have what is called inactive or latent TB infection, where the bacteria remain in the body without causing symptoms. These people do not have TB disease and do not spread TB to others. However, latent infection can sometimes progress to active disease.

The risk of developing active disease is higher in people with conditions or circumstances that weaken the immune system, including diabetes, undernutrition and certain immune-suppressing conditions. Tobacco use can also increase the risk.

Tuberculosis symptoms to watch for

The symptoms of active TB can develop gradually, and some may be mild initially. Common symptoms include:

  • A cough that lasts for several weeks
  • Chest pain
  • Coughing up sputum or, sometimes, blood
  • Fever
  • Sweating at night
  • Unexplained weight loss
  • Loss of appetite
  • Weakness or unusual tiredness

A persistent cough, especially when accompanied by weight loss, fever or night sweats, deserves medical attention. According to the CDC(Centers for Disease Control and Prevention), a cough lasting three weeks or longer can be a symptom of pulmonary TB.

However, these symptoms do not necessarily mean that a person has TB. Several other infections and lung conditions can cause similar problems. Testing is needed to establish the diagnosis.

Can TB affect other parts of the body?

Yes. Although the lungs are the most commonly affected organs, TB can occur outside the lungs, known as extrapulmonary TB.

The symptoms depend on which part of the body is affected. For example:

  • Lymph nodes: swelling or a lump, often in the neck
  • Kidneys: blood in the urine or urinary symptoms
  • Spine: persistent back pain
  • Brain: headache, confusion or other neurological symptoms
  • Larynx: persistent hoarseness

How is tuberculosis diagnosed?

Doctors do not diagnose TB based on symptoms alone. Depending on the person's symptoms and medical history, evaluation may include:

Medical history and examination: The doctor may ask about symptoms, previous TB exposure, existing medical conditions and other factors that may increase the risk of TB.

Chest imaging: A chest X-ray may be used when pulmonary TB is suspected. It can show changes in the lungs that need further evaluation, but imaging alone cannot confirm TB.

Sputum testing: For suspected pulmonary TB, a sample of sputum may be tested for TB bacteria. WHO recommends rapid diagnostic tests as initial tests for people with signs and symptoms of TB.

Laboratory testing can include molecular tests, microscopy and culture. Testing may also help determine whether the bacteria are resistant to particular medicines.

TB blood or skin tests: TB blood tests and skin tests can help identify TB infection. A positive result does not by itself tell doctors whether the person has inactive TB infection or active TB disease. Further medical evaluation is needed.

When should you see a doctor?

Consider medical evaluation if you have a cough that persists for several weeks, particularly if it occurs with:

  • Unexplained weight loss
  • Persistent or recurring fever
  • Night sweats
  • Chest pain
  • Coughing up blood
  • Marked tiredness or weakness

You should seek urgent medical attention if you cough up a significant amount of blood, have severe difficulty breathing, experience severe chest pain or become confused or very unwell. If you have been in close contact with someone diagnosed with infectious TB, speak to a healthcare professional about whether you need testing, even if you feel well.

Can tuberculosis be treated?

Yes. TB is preventable and curable when appropriately diagnosed and treated. Treatment involves specific antibiotics, and the medicines and duration depend on whether the person has TB infection or active disease and whether drug resistance is present.

It is important to take TB medicines exactly as prescribed. Stopping treatment early or taking medicines incorrectly can make treatment less effective and may contribute to drug resistance.

Conclusion

TB does not always begin with severe symptoms. A cough that persists, unexplained weight loss, fever, night sweats or coughing up blood should not be dismissed, particularly when symptoms continue or worsen.

Recognising the warning signs and getting the right tests can help identify TB and other possible causes early. If you have persistent symptoms or have been exposed to someone with TB, speak with a healthcare professional rather than trying to diagnose yourself.

How PB Health can support you

Persistent cough, unexplained weight loss, fever or other concerning symptoms can have several possible causes. PB Health Hospital, IFFCO Chowk, Gurgaon can help connect you with the appropriate doctor, including a pulmonologist Gurgaon, who can review your symptoms, medical history and available reports and guide you on the next steps, including whether further testing is needed.